I've heard that Ketu in the 12th House signifies Moksha, and the possibility that this life might be the last one. Is it really so? What other factors are to be taken into account? I also have Saturn with Ketu in my 12th House. Would that be a hindrance?
Check whether this Ketu has got an aspect from Jupiter. if there is any, then, this may be the last birth.
8th house indicates time of death or total life span.
12th house indicates soul's interested path/journey after death.
if Ketu is in 12 with an aspect from Jupiter, then soul never likes to reincarnate again, and travels to supreme soul.